Recombinant Human Epidermal Growth Factor (EGF)
Recombinant Human Basic Fibroblast Growth Factor (bFGF)
Recombinant Human Insulin-like Growth Factor (IGF-1)
Recombinant Bovine Basic Fibroblast Growth Factor（rbbFGF）
1. No animal origin, no pathogenic substances.
2. High security, high purity, high specific activity, and high catalytic efficiency.
3. Production equipment and production environment comply with relevant regulatory requirements and GMP standard.
4. Provide finished and complete quality and relevant regulatory documents.
Topical growth factors work by mimicking the body's natural signaling processes to tell skin cells to perform specific actions. When applied to the skin, GFs don't penetrate deeply into the bloodstream; instead, they interact with specific receptors located on the surface of various skin cells, such as fibroblasts and keratinocytes. This interaction triggers a cascade of biochemical events (a signal transduction pathway) inside the cell.
Growth factor means a group of proteins that stimulate the growth of the cell, usually it functions as hormone-like regulatory signals, controlling the growth and differentiation of responsive cells.
Growth factors bind to receptors on the cell surface, with the result of activating cellular proliferation and/or differentiation.
Growth factors regulate the cell cycle by initiating various signaling pathways. These signalling pathways are mediated by the binding of growth factors into their corresponding epidermal growth factor receptor, and include the Ras/Erk pathway and PI3K/Akt pathway.
Yes, topical growth factors are considered safe for cosmetic use and are not known to increase cancer risk. Growth factors are large molecules that work only on the surface layers of the skin. They are designed to promote controlled repair and regeneration of healthy cells, not systemic changes.
Growth factors (GFs) used in skincare are generally sourced from three sources:
Recombinant / Bioengineered Sources: Use advanced technology to synthesize human-identical cell growth factors in a lab (often using non-animal systems like barley or yeast). This ensures the highest purity and eliminates contamination risks.
Human Cell Cultures : These GFs are collected from the nutrient fluid used to culture human cells. They offer a comprehensive mix of natural growth signals.
Plant and Animal Derivatives: These sources, such as certain plant extracts or snail mucin, contain natural compounds that possess strong growth factor-like properties, offering excellent skin repair benefits.