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Difference Between Biologics and Bio-pharmaceuticals

Published Date: Dec 02 2022


The difference between biological preparations and bio-pharmaceuticals is that biological preparations are not only different in raw materials from generic drugs, but also in the production process. To put it simply, it is the use of modern biotechnology to produce the required medicines with the help of certain microorganisms, plants, or animals, and the protein or nucleic acid drugs developed by DNA recombination technology or other biological new technologies also become biological preparations. It is a pure biological preparation, which means that it does not contain traditional chemicals except excipients. The earliest biological drug was insulin in 1982. At present, there are only about 50 kinds of biological preparations approved for marketing at home and abroad, and there are hundreds of kinds under research, which is a very popular subject.


Bio-pharmaceuticals refer to a class of drugs for disease prevention and treatment obtained from animals, plants, microorganisms, and other organisms through biotechnology such as separation and extraction, biosynthesis, biochemical synthesis, and DNA recombination. Bio-pharmaceutical raw materials are mainly natural biological materials, including microorganisms, the human body, animals, plants, marine organisms, etc. With the development of biotechnology, purposefully prepared biological raw materials have become the main source of current bio-pharmaceutical raw materials. Biological drugs mainly include proteins, nucleic acids, carbohydrates, lipids, etc. The constituent units of these substances are biochemical substances such as amino acids, nucleosides, nucleotides, their derivatives, polypeptides, enzymes, coenzymes, lipids, and polysaccharides. In addition, the management of the use of biologics and bio-pharmaceuticals is also different. For all biological products, users should take them with a doctor's prescription, but some biochemical drugs are over-the-counter drugs and can be purchased and used without a doctor's prescription.

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All products from the site for Research Use Only. Not for use in diagnostic procedures. Reproduction of any materials is strictly forbidden without permission.